IDRI Makes Strides in Vaccine Technology, New Study in Science Translational ...
/PRNewswire-USNewswire/ -- The Infectious Disease Research Institute (IDRI), International Centre for Genetic Engineering and Biotechnology (ICGEB) and Imdaptive Inc. announce new research that for the first time shows how to define how vaccine components expand immune responses. The results of these studies are published in Science Translational Medicine today.The research was performed by scientists at IDRI in collaboration with researchers at ICGEB, . They demonstrated that increased variable chain sequences are observed in animals treated with a recombinant malaria vaccine formulated with immune response enhancers, TLR-agonists, versus animals receiving control vaccines. This diversity, or "antibody repertoire," may have the most significant impact on the vaccine's efficacy against a target pathogen as well as related variants.
Dr. , Vice President of Adjuvant Technology at IDRI and one of the study's Principal Investigators, explains, "By measuring the entire antibody variable repertoire, we are able to show that antibody diversity is a function of the adjuvants used to initiate and enhance the immune response. This knowledge has the potential to make a significant impact on the future of vaccine design."
Dr Adjuvants are compounds used to improve the body's immune response to vaccines. Adjuvant technology is proving invaluable in the development of vaccines for serious diseases for which vaccines are not currently available, including malaria and HIV.
Adjuvants are a key research component of IDRI's malaria, tuberculosis, leishmaniasis and leprosy vaccine development programs—supported by the Bill and Melinda Gates Foundation, the National Institutes of Health, and the American Leprosy Missions.
About IDRI – Translating science into global health solutions
IDRI is a -based not-for-profit organization committed to applying innovative science to the research and development of products to prevent, detect, and treat infectious diseases of poverty. By integrating capabilities—including preclinical vaccinology, manufacturing, and clinical trials—IDRI strives to create an efficient pathway bringing scientific innovation from the lab to the people who need it most.
For more information, go to www.idri.org .
Contact: is focused on addressing problems in health and agriculture. Health related projects are pursued in hepatitis B and E virus, HIV, tuberculosis, dengue and malaria. Plant biology projects address biopesticides, abiotic and biotic plant stress and crop improvement through biotransformation.
American Leprosy Missions - News
Adjuvants are a key research component of IDRI's malaria, tuberculosis, leishmaniasis and leprosy vaccine development programs—supported by the Bill and Melinda Gates Foundation, the National Institutes of Health, and the American Leprosy Missions.
Community nurses trained to detect leprosy, tuberculosis and other chronic diseases patiently listened to Ms Merchant's halting Kannada, the main language used in the area, as she explained how to handle the new medical equipment.
By day, he performed emergency surgeries, delivered babies and treated people with infectious diseases such as malaria and leprosy. “I absolutely feel needed and useful. People are so grateful and caring. There's no threats of lawsuits,” he said.
The parents of this patient came to us seeking to try a new drug … What they got was a small amount of penicillin … They paid 5000 Chet ($ 7.14) but it did not work … We tried and tried to help this particular leper. So I prayed to St. Anthony …
He also recognized his own mission—which fueled his rise on July 1 to governor of District 5340. He called the district “one of the finest” in Rotary, generating $1.3 million a year in grants toward projects around the world. He called La Mesa Sunrise
Bill Simmons – American Leprosy Missions | Quest for Character ...
, Bill Simmons.
Bill is passionate about the mission of ALM. He sets the pace of the organization, helping to maximize the potential of the ALM team. He brings more than twenty years of management experience to his role having served as President and CEO of two nationwide, Christian, retail chains.
Born in Tennessee, Bill spent his teenage years in the Democratic Republic of the Congo (then Zaire), where his parents were missionaries. He graduated from the University of Tennessee with a degree in political science. Bill has served on the boards of several non-profit organizations. He thinks nothing of a quick lunchtime bike ride to the top of nearby Paris Mountain and back. An avid photographer, Bill returns from every trip to the field with photos showing both the deep need and God’s stunning grace at work through the ministry of ALM.
American Leprosy Missions, based in Greenville, South Carolina, is the oldest and largest Christian organization in the United States dedicated to touching, treating and transforming the lives of people affected by leprosy and related diseases.
Collaborating with other international organizations, ALM currently supports 38 projects in 15 countries in Africa, Asia and South America. During its more than 100-year history, ALM has provided holistic care to 4 million people around the world including medical treatment and training, Christian outreach, prevention of disability, community development, education assistance, micro-credit loans and vaccine research.
American Leprosy Missions - Bookshelf
The work of the Mission to Lepers, a statement showing the extent and nature of operations; and its relation to other organizations in its world-wide field
The American Mission to Lepers, Inc, U.S.A. news notes
Handbook of American resources for African studies
AMERICAN LEPROSY MISSIONS, INC. American Leprosy Missions, Inc., 297 Park Avenue South, New York, New York 1 00 10, was organized in 1906 to give aid to the ...An invitation to affiliate with the mission to lepers
U.S. non-profit organizations, voluntary agencies, missions and foundations participating in technical assistance abroad
AMERICAN LEPROSY MISSIONS, INC. 297 Park Avenue South - New York, New York 10010 - GR 5-5854 OTHER US OFFICES FOUNDED EXECUTIVE STAFF OBJECTIVES ASSISTANCE ...Helpful Information Directory
American Leprosy Missions
Provides care to people around the world with leprosy and related disabilities. Includes news, descriptions of current projects, and information on how people can help.
American Leprosy Missions | Aid for Africa
American Leprosy Missions has been caring for people affected by leprosy, Buruli ulcer and related conditions in Africa for more than 50 years, providing both
American Leprosy Missions | Facebook
Welcome to the official Facebook Page of American Leprosy Missions. Get exclusive content and interact with American Leprosy Missions right from Facebook. ...
Charity Navigator Rating - American Leprosy Missions
Mission. Founded in 1906, American Leprosy Missions (ALM) provides care to people around the world with leprosy and with Buruli ulcer and related disabilities. ...
Charity Review of American Leprosy Missions
American Leprosy Missions. BBB Wise Giving Report issued April 2011 ... ALM covers costs of treating leprosy in countries in Africa, Asia, and South ...